KN-93 Phosphate B

CAS No. 1913269-12-1

KN-93 Phosphate B( —— )

Catalog No. M34125 CAS No. 1913269-12-1

KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 67 Get Quote
5MG 93 Get Quote
10MG 140 Get Quote
25MG 273 Get Quote
50MG 509 Get Quote
100MG 718 Get Quote
500MG 1431 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    KN-93 Phosphate B
  • Note
    Research use only, not for human use.
  • Brief Description
    KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM.
  • Description
    KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    CaMK
  • Recptor
    CaMK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1913269-12-1
  • Formula Weight
    599.03
  • Molecular Formula
    C26H32ClN2O8PS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (166.94 mM; Ultrasonic )H2O : 50 mg/mL (83.47 mM; Ultrasonic)
  • SMILES
    OP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c1ccccc1CN(C)C\C=C\c1ccc(Cl)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tombes RM, et al. G1 cell cycle arrest and apoptosis are induced in NIH 3T3 cells by KN-93, an inhibitor of CaMK-II (the multifunctional Ca2+/CaM kinase). Cell Growth Differ. 1995 Sep;6(9):1063-70.?
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